Gene and Products: ITPKC inositol-trisphosphate 3-kinase C [Homo sapiens]. Summary; mRNA and Protein(s); References; Additional Links

5 Mar 2021 ITPKC (Inositol-Trisphosphate 3-Kinase C) is a Protein Coding gene. Diseases associated with ITPKC include Kawasaki Disease and Coronary

Isotipo, IgG. Método de purificación, Antigen Affinity In this article, I review the candidate gene association studies to date. We investigated mRNA expression of ITPKC in various normal tissues and revealed that 21 Mar 2020 Pointers that suggest a genetic basis of KD include a high disease prevalence Onouchi et al. found ITPKC as the potential candidate gene for 18 Aug 2020 The ITPKC gene provides instructions for making one version (isoform) of the inositol 1,4,5-trisphosphate 3-kinase (ITPK) enzyme. This enzyme review revealed numerous potential susceptibility genes including genetic polymorphisms of ITPKC,. CASP3, the transforming growth factor-β signaling pathway Names & Symbols · PharmGKB ID · HGNC Approved Name · Alternate Names · Alternate Symbols. Gene and Products: ITPKC inositol-trisphosphate 3-kinase C [Homo sapiens].

Itpkc gene

Inositol 1,4,5-trisphosphate (IP3) 3-kinase C (ITPKC) is a negative regulator of the SOC channel-mediated signaling pathway. We investigated the association between calcium containing nephrolithiasis and genetic variants of ITPKC gene in Taiwanese patients. 365 patients were recruited in this study. ITPKC gene expression among cells in the tumor microenvironment. Boxplots of the ITPKC gene expression by cancer cells, stromal cells, T cells, B cells and myeloid cells in single-cell sequencing data of primary breast cancer in GSE75688. One-way ANOVA test was used to calculate p values.

Inositol 1,4,5-trisphosphate 3-kinase (ITPK) catalyzes the phosphorylation of Ins (1,4,5)P3 to Ins (1,3,4,5)P4, both of which are modulators of calcium homeostasis.

(from RefSeq NM_025194) Summaries for ITPKC gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL) About This Sectio General information; Gene symbol: ITPKC: Gene name: inositol-trisphosphate 3-kinase C: Chromosome: 19: Chromosomal band: q13.1: Imprinted: Unknown: Genomic reference ITPKC: Gene description i. Inositol-trisphosphate 3-kinase C: Protein class i.

identification of 2-locus genes interaction model. RESULTS: A significant combinatorial association between ITPKC. (rs28493229) and CASP3( rs72689236)

17 Jan 2019 PKAN, is caused by mutations in the PANK2 gene and is thought to reduce CoA in neurons. The PZ-2891 compound temporarily locks ALK · BCL-2 · CD79b · HER Pathways · MAPK · MDM2 · NTRK Gene Fusions · PI3K/AKT Pathway · Explore ROS1 · VEGF · The Hallmarks of Cancer. 16 May 2020 It is believed that an infectious trigger in those with a genetic predisposition Genetics: The ITPKC gene may play a role in Kawasaki disease, 20 Nov 2019 In another study conducted by Kuo et al, they noticed that high-risk genotype patients with combined acquisition of ITPKC gene (rs28493229) 4 Nov 2018 genome-wide association studies (GWASs) have been conducted ITPKC gene SNP rs28493229 and Kawasaki disease in Taiwanese.

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Kawasaki disease is an acute febrile illness that involves the inflammation of blood vessels throughout the body.

genes associated with KD.5 One of the most interesting candi-date genes is inositol-1,4,5-triphosphate 3-kinase (ITPKC), which was first reported in Japan.6 Different single-nucleotide polymorphisms (SNPs) in the ITPKC gene have been reported in several countries.2,7 However, a previous study found no polymorphisms in ITPKC in Korean KD patients.
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Inositol 1,4,5-trisphosphate (IP3) 3-kinase C (ITPKC) is a negative regulator of the SOC channel-mediated signaling pathway. We investigated the association between calcium containing nephrolithiasis and genetic variants of ITPKC gene in Taiwanese patients. 365 patients were recruited in this study.

ITPKC gene product. IP3-3KC, IP3KC. This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the itpkc inositol-trisphosphate 3-kinase C This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The gene ITPKC may have Genomic and Proteomic products available from Sigma-Aldrich. 2019-12-07 · [PMID 18084290] ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms. [PMID 20805785] Clinical Implication of the C Allele of the ITPKC Gene SNP rs28493229 in Kawasaki Disease: Association With Disease Susceptibility and BCG Scar Reactivation. 320404 Ensembl ENSG00000143772 ENSMUSG00000038855 UniProt P27987 B2RXC2 RefSeq (mRNA) NM_002221 NM_001388404 NM_001081175 RefSeq (protein) NP_002212 NP_001074644 Location (UCSC) Chr 1: 226.63 – 226.74 Mb Chr 1: 180.33 – 180.42 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Inositol-trisphosphate 3-kinase B is an enzyme that in humans is encoded by the ITPKB gene.

Genetic polymorphisms of the ITPKC signaling pathway in Kawasaki disease. A major advancement in the genetic study of KD was made by the discovery of

Function The 2021-02-20 · Known as: IP3KC, ITPKC, IP3-3KC Expand This gene plays a role in both second messenger metabolism and calcium homeostasis. National Institutes of Health Create Alert The gene ITPKC may have Genomic and Proteomic products available from Sigma-Aldrich.

General information; Gene symbol: ITPKC: Gene name: inositol-trisphosphate 3-kinase C: Chromosome: 19: Chromosomal band: q13.1: Imprinted: Unknown: Genomic reference genes associated with KD.5 One of the most interesting candi-date genes is inositol-1,4,5-triphosphate 3-kinase (ITPKC), which was first reported in Japan.6 Different single-nucleotide polymorphisms (SNPs) in the ITPKC gene have been reported in several countries.2,7 However, a previous study found no polymorphisms in ITPKC in Korean KD patients. Summaries for ITPKC gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL) About This Sectio Phenotype data for mouse gene Itpkc. Discover Itpkc's significant phenotypes, expression, images, histopathology and more.